BDBM11694 (2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidine-2-carbonitrile::BMCL15687 Compound 3::CHEMBL307636::Cyclohexylglycine-(2S)-cyanopyrolidine 3::Cyclohexylglycine-(2S)-cyanopyrrolidine 2

SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=SXNUNNAPZNTPQV-RYUDHWBXSA-N

Data  3 KI  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 11694   

TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  3.99E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  1.02E+5nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase II (DPP II) obtained form bovine kidney homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  4.10E+4nMAssay Description:In vitro inhibitory activity against Post-proline cleaving enzyme (PPCE) obtained from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  3.99E+4nMAssay Description:Inhibitory concentration against DPP-II [Quiescent cell proline dipeptidase] or DPP-VIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11694((2S)-1-[(2S)-2-amino-2-cyclohexylacetyl]pyrrolidin...)
Affinity DataIC50:  3.99E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed